PI3K‐R1 expression in hepatic tissue of horses with laminitis
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چکیده
منابع مشابه
Vascular Dysfunction in Horses with Endocrinopathic Laminitis
Endocrinopathic laminitis (EL) is a vascular condition of the equine hoof resulting in severe lameness with both welfare and economic implications. EL occurs in association with equine metabolic syndrome and equine Cushing's disease. Vascular dysfunction, most commonly due to endothelial dysfunction, is associated with cardiovascular risk in people with metabolic syndrome and Cushing's syndrome...
متن کاملComparison of first and second acupuncture treatments in horses with chronic laminitis
Background: Laminitis is a common but critical disease that causes severe pain and disability in horses. The etiology and pathogenesis of laminitis remain inconclusive and a multimodal therapeutic approach is generally indicated. Acupuncture has been used as a treatment option; however, the required number of treatments is still controversial due to the lack of objective scient...
متن کاملAre Drugs Effective Treatment for Horses With Acute Laminitis?
Currently, the only therapy for horses with acute laminitis for which there is consensus among practitioners is aggressive treatment for the disease process that has initiated laminitis. Although other treatments may have merit and seem logical based on studies of the pathogenesis of laminitis, the efficacy of these treatments has not been proven. Some of the confusion regarding treatment of ho...
متن کاملThe Prevalence and Histopathology of Endocrinopathic Laminitis in Horses
................................................................................................ 5 ACKNOWLEDGEMENTS .......................................................................... 7 CONTENTS ................................................................................................ 9 LIST OF ORIGINAL PUBLICATIONS ..................................................... 12 ABBREVIAT...
متن کاملExpression and Activity of Collagenases in the Digital Laminae of Horses with Carbohydrate Overload-Induced Acute Laminitis
BACKGROUND Matrix metalloproteinases (MMP) are hypothesized to degrade structurally important components of the laminar extracellular matrix (ECM) in horses with laminitis. OBJECTIVE To compare levels of expression of stromelysin-1 (MMP-3), collagenases (MMP-1, -13), and membrane type-MMPs (MMP-14, -15, -16), and the distribution of their ECM substrates, in laminae of healthy horses and horse...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2009
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.23.1_supplement.929.2